49ers Schedule 2025 Preseason Games. Nine weeks ago, we were staring at a blank slate of 272 games, wondering. The san francisco 49ers have announced their 2025 regular season schedule as well as the opponents and date ranges for the team's three preseason games.

San francisco will have one preseason home game sandwiched between a couple of road. View the 2025 san francisco 49ers schedule, results and scores for regular season, preseason and postseason nfl games.